Attachment of Respiratory Pathogens and Candida to Denture Base Materials—A Pilot Study

Denture prostheses are an ideal and extensive reservoir for microorganisms to attach their surfaces. The aim of the study was elucidate interactions between materials fabrication denture bases attachment microorganisms, focusing on respiratory pathogens Candida species. Specimens (6 mm × 1 mm) with a standardized surface roughness (Sa = 0.1 µm) were prepared from heat-pressed polymethyl methacrylate (PMMA), CAD/CAM-processed PMMA, polyether ether ketone (PEEK). specimens randomly placed in vestibular areas complete upper dentures seven patients removed either after 24 h without any oral hygiene measures or period four weeks. adherent cultivated subsequently analyzed using mass spectrometry (MALDI-TOF). means standard deviations calculated, data two-way analysis variance (ANOVA) Tukey post-hoc test where appropriate (α 0.05). There significant increase (p ≤ 0.004) total bacterial counts (CFU/mL) first (24 h) second (four weeks) measurements. Regarding quantitative microbiological analyses, no differences various identified. Respiratory detected all samples at both measurement time points, large different patients. Only weeks, species identified but not participants. accumulate base resins. While materials, there tendency towards more pronounced accumulation conventionally processed PMMA.